| 04/10/08 | Lorient Ciani 58 | 1-2 | Bordeaux Menegazzo 67, 68 |
| 04/10/08 | Marseille Ben Arfa 2, Niang 60 | 2-1 | Caen Savidan 20 |
| 04/10/08 | Nice Echouafni 50 | 1-1 | Sochaux Birsa 73 |
| 04/10/08 | Toulouse Gignac 56 | 1-0 | Auxerre |
| 04/10/08 | Grenoble Foot 38 | 0-1 | FC Nantes Bekamenga 77 |
| 04/10/08 | Le Havre Alassane 13 | 1-2 | Le Mans Maiga 89, Gervinho 90 |
| 04/10/08 | Lille Abardonado 69(o) | 1-0 | Valenciennes |
| 05/10/08 | Rennes Pagis 17, 56, 67 | 3-0 | Lyon |
| 05/10/08 | AS Saint-Etienne Gomis 11, Dernis 83 | 2-0 | Monaco |
| 05/10/08 | Nancy | - | PSG |
| 18/10/08 | Caen | - | Grenoble Foot 38 |
| 18/10/08 | Sochaux | - | Le Havre |
| 18/10/08 | Monaco | - | Nice |
| 18/10/08 | Bordeaux | - | Toulouse |
| 18/10/08 | PSG | - | Lorient |
| 18/10/08 | FC Nantes | - | AS Saint-Etienne |
| 18/10/08 | Lyon | - | Lille |
| 19/10/08 | Auxerre | - | Rennes |
| 19/10/08 | Le Mans | - | Nancy |
| 19/10/08 | Valenciennes | - | Marseille |
| 25/10/08 | Rennes | - | Le Mans |
| 25/10/08 | Marseille | - | PSG |
| 25/10/08 | Nancy | - | Sochaux |
| 25/10/08 | Auxerre | - | Lyon |
| 25/10/08 | Nice | - | Bordeaux |
| 25/10/08 | Lille | - | Caen |
| 25/10/08 | Le Havre | - | Valenciennes |
| 25/10/08 | Toulouse | - | Monaco |
| 25/10/08 | Lorient | - | FC Nantes |
| 25/10/08 | AS Saint-Etienne | - | Grenoble Foot 38 |
| 29/10/08 | Monaco | - | Nancy |
| 29/10/08 | Valenciennes | - | Rennes |
| 29/10/08 | Caen | - | Nice |
| 29/10/08 | Bordeaux | - | Le Havre |
| 29/10/08 | Grenoble Foot 38 | - | Lille |
| 29/10/08 | FC Nantes | - | Marseille |
| 29/10/08 | AS Saint-Etienne | - | Lorient |
| 29/10/08 | Le Mans | - | Auxerre |
| 29/10/08 | PSG | - | Toulouse |
| 29/10/08 | Sochaux | - | Lyon |
