| 03/10/08 | Arminia Herzig 86 | 1-2 | Karlsruhe Porcello 16, Freis 52 |
| 04/10/08 | VfB Stuttgart Khedira 18, Trasch 29, Hilbert 63, Lanig 88 | 4-1 | Bremen Diego 65 |
| 04/10/08 | Mönchengladbach Brouwers 11 | 1-2 | Köln Ehert 5, Novakovic 88 |
| 04/10/08 | Hoffenheim Ba 46, 72 | 2-1 | Eintracht Steinhofer 67 |
| 04/10/08 | Leverkusen | 0-1 | Hertha BSC Berlin Voronin 89 |
| 04/10/08 | Bayern Van Buyten 15, Ze Roberto 45, 68 | 3-3 | Bochum Kaloglu 29, Dabrowski 84, Grote 85 |
| 05/10/08 | Schalke Kuranyi 20, 90 | 2-2 | VfL Wolfsburg Dzeko 51, Caiuby 65 |
| 05/10/08 | BV Borussia Dortmund Valdez 10 | 1-1 | Hannover Forssell 25 |
| 05/10/08 | Energie Jelic 74 | 1-2 | Hamburg Olic 54, Petric 90 |
| 17/10/08 | Bochum | - | Mönchengladbach |
| 18/10/08 | Köln | - | Energie |
| 18/10/08 | Hannover | - | Hoffenheim |
| 18/10/08 | VfL Wolfsburg | - | Arminia |
| 18/10/08 | Hertha BSC Berlin | - | VfB Stuttgart |
| 18/10/08 | Karlsruhe | - | Bayern |
| 18/10/08 | Bremen | - | BV Borussia Dortmund |
| 18/10/08 | Eintracht | - | Leverkusen |
| 19/10/08 | Köln | - | Energie |
| 22/10/08 | Eintracht | - | Karlsruhe |
| 25/10/08 | Hannover | - | Bremen |
| 25/10/08 | Schalke | - | Arminia |
| 25/10/08 | VfB Stuttgart | - | Bochum |
| 25/10/08 | Hoffenheim | - | Hamburg |
| 25/10/08 | Leverkusen | - | Köln |
| 25/10/08 | Energie | - | Eintracht |
| 25/10/08 | Mönchengladbach | - | Karlsruhe |
| 25/10/08 | BV Borussia Dortmund | - | Hertha BSC Berlin |
| 25/10/08 | Bayern | - | VfL Wolfsburg |
| 29/10/08 | Hamburg | - | VfB Stuttgart |
| 29/10/08 | Karlsruhe | - | Schalke |
| 29/10/08 | Bremen | - | Leverkusen |
| 29/10/08 | Arminia | - | Energie |
| 29/10/08 | Köln | - | BV Borussia Dortmund |
| 29/10/08 | Bochum | - | Hoffenheim |
| 29/10/08 | Eintracht | - | Bayern |
| 29/10/08 | VfL Wolfsburg | - | Mönchengladbach |
| 29/10/08 | Hertha BSC Berlin | - | Hannover |
